Antidepressant Use and Depression Symptoms in Pregnancy

Timeframe

2021–2023

Funding

COMPASS staff

Stephanie D’Souza

Collaborators

University of Auckland
Karen Waldie

University of Canterbury
Julia Rucklidge

Students & Research Assistants

Francesca Anns, BA(Hons) and RA
Charlotte Svardal, RA
Dilpreet Kaur, Summer Scholar

Description

This project aimed to address the need for more evidence that both depression and antidepressant use during pregnancy are associated with adverse birth and later child outcomes. Evidence was previously mixed with regard to antidepressant use, with more information needed on whether it posed a greater risk of adverse outcomes than unmedicated maternal depression.

We examined data on antidepressant use and depressive symptoms in pregnant mothers from the Growing Up in New Zealand (GUINZ) study, and looked at how these related to outcomes for their offspring through 8 years of age. We made specific distinctions among mothers taking antidepressants, those with unmedicated depression, and those in neither of these situations.